An improved synthesis of 1-methylcyclopropanol using the Kulinkovich reaction

Abstract:

An improved process for the preparation of 1-methylcyclopropanol using the Kulinkovich reaction is described. The use of titanium tetramethoxide as catalyst resulted in minimal side product formation. The reaction, isolation and purification procedures were optimized so they can be easily implemented in multi-purpose equipment.

Graphical Abstract 

Access the full article now

Source: Bioorganic & Medicinal Chemistry, Volume 26, Issue 4, 15 February 2018, Pages 984-988
Authors: Christine Delsarte, Guillaume Etuin, Laurent Petit
Minakem Recherche, 145 chemin des Lilas, 59310 Beuvry-La-Forêt, France

Feel free to get in contact with our technical team: contact form

Stay in touch? Leave us your e-mail address to receive our latest news

Subscribe

News Request