FRANCE
Beuvry-la-Foret
Our Beuvry la Foret site offers process and analytical development, scale-up and manufacturing capabilities for custom synthesis and small molecules APIs.
We have extensive experience of process design as our main R&D center is located here, working together with our industrialization and project management team for successful scale-up and cGMP production from grams to tons of your APIs and key intermediates for multistep synthesis.
Our team can also offer regulatory filling support for the US, EU, Japan and China.
Key Facts
- R&D Center of Excellence
- cGMP kilolab and pilot plant
- 122 m3 reaction capacity: multipurpose and highly flexible range of technologies
- State-of-the-art API facility fully automated started in 2024
Compliance approvals
FDA / ANSM (EU/France) / Japan
Facility details
Process chemistry development laboratories
R&D analytical development and QC laboratories
Corrosion resistant Kilo lab with 20-40 liters reactors and filter dryer
Small scale:
- reactors from 60 to 630 liters glass lined, stainless steel or Hastelloy®,
- centrifuge and filter dryer in ISO 8 isolation and drying suites
Production capacities:
- 49 reactors from 630 to 6300 liters glass lined, stainless steel or Hastelloy® in 4 separate modules
- centrifuges – filter dryers – dryers – tray dryers – milling in ISO 8 isolation and drying suites
Core capabilities
- cGMP custom synthesis from kilo-lab to multi-ton scale
- Complex Multi-step API process development, manufacturing and analytical development
- Industrialization from feasibility to commercial scale
- Process Continuous Improvement
- Hydrogenation
- Chlorination
- Bromination
- Cyanidation
- Lithiation
- Boronic acids
- Carboxylation
- Chiral synthesis
- Cryo technology (-80°C)
Dunkerque – France
Commercial production of small molecule APIs
- Large scale manufacturing
Montreal – Canada
Development and commercial production of small molecule APIs and Steroids
- Fit for purpose process and analytical development with timely and robust scale-up from clinical to commercial supply
- Dedicated steroid manufacturing unit
Louvain-la-Neuve – Belgium
Development and commercial production of small molecule Highly Potent APIs (HPAPIs) and Steroids
- Fit for purpose process and analytical development with timely and robust scale-up from clinical to commercial supply
- OEL: 0.1µg/m3/shift and Industrial Preparative HPLC
Beuvry-la-Foret – France
Development and commercial production of small molecule APIs
- Fit for purpose process and analytical development with timely and robust scale-up from clinical to commercial supply
- Home to Minakem’s R&D Center of Excellence